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Drews, Barabara, Goritz, F., Hermes, R., Striech, J.W., Rich, P., Schmitt, D., Lung, N., Renfree, M., gaeth, A.P., Short, R.V., and Hildebrandt, T.B. Morphologicial and ultrasonographic characteriazation of the embryonic development in elephants. International Elephant Conservation and Research Symposium, Copenhagen, Demark, 2006 Abstract and presentation ; Schmitt D.L. Under the Big Top. Why elephants belong in circuses. In: Ethics of Elephants in Captivity. C. Cristen ed. John Hopkins University Publishing. In Press. Schmitt D.L., Lindsay, W.A., Wiedner, E., Kiso, W.K. Use of Equine Seminal Plasma to initiate motility in Asian elephant semen. Proc. Elephant Managers Association. Portland, OR 2005 Jayaram, J., Cheeran, J., Panakur, A.J., and Schmitt D.L. Tuberculosis in Temple elephants in Kerala, India. Proc. Elephant Managers Association, Portland, OR 2005 Schmitt D.L., Lindsay, W.A., Wiedner, E., Kiso, W.K. Use of Equine Seminal Plasma to initiate motility in Asian elephant semen. Proc. Society of Theriogenology. Charleston, SC. 2005. Miller, M., Neiffer, D., Schmitt, D., Weber, M., Robbins, P.K., Stetter, M., Fontenot, D., Fleming, D., Bolling, J., Miller, G., Malu, P., Medical Management of dystocia and vestibulotomy for removal of a retained fetus in an African elephant. International Elephant Research Symposium 2004 ; Lindsay, W.A., Schmitt, D.L., Jacobson, G., Endosurgical reduction of a vaginal cyst in an Asian elephant. International Elephant Research Symposium 2004 ; Kiso, W., Schmitt, D., Lindsay, W., Comparison of acrosome status in Asian Elephas maximus ; and African Loxodonta Africana ; elephant sperm using spermac stain. International Elephant Research Symposium 2004 ; Kinchen, K., Schmitt, D. Gonadotrophin activity in serum from pregnant Asian elephants Elephas maximus ; . International Elephant Research Symposium 2004 ; Poster. Brown, J.L., and Schmitt, D.L. The unusual anatomy and reproductive physiology of the elephant, and challenges with developing artificial insemination. Science India 7: 9 & 10 2732 2004 ; . Brown, J. L., Goritz, F, Pratt-Hawkes, N., Hermes, R., Galloway, M., Graham, L. H., Gray, C., Walker, S. L., Gomez, A., Moreland, R., Murray, S., Schmitt, D. L., Howard, J., Lehnhardt, J., Beck, B., Bellem, A., Montali, R., and Hildebrandt, T. B. Successful artificial insemination of an Asian elephant at the National Zoological Park. Zoo Biology 23[1], 45-63. 2004. Dahl, N.J., Olson, D., Schmitt, D.L., Blasko, D.R., Kristipati, R.S., and Roser, J.F. Development of an Enzyme-Linked Immunosorbent Assay ELISA ; in the Elephant Loxodonta africana and Elephas maximus ; Zoo Biology 23: 65-78 2004 ; Schmitt, D. Ultrasonography of Elephants In: Health Care, Breeding and Management of Asian 5.
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277 FLUID TRANSPORT IN THE RAT UTERUS DURING EARLY PREGNANCY L. A. Lindsay, C. R. Murphy School of Medical Sciences Anatomy and Histology ; , The University of Sydney, NSW, Australia Implantation of the rat blastocyst is a highly regulated process, involving conversion of the uterine environment into one which is receptive to an implanting blastocyst. Part of this process involves a change in the fluid dynamics of the uterus during implantation, going from a lumen full of fluid on day 1 of pregnancy to close apposition between the luminal epithelium and trophoblastic cells at the time of implantation. Currently mechanisms regulating this change in luminal fluid volume are unknown. Aquaporins, a family of transmembrane water channels, are involved in the regulation of water movement across epithelial barriers. We investigated several aquaporins in the rat uterus during early pregnancy using reverse transcriptase PCR and found the presence of AQP1, AQP5, AQP7, AQP8 and AQP9. Immunofluorescence and immunogold electron microscopy techniques were then used to investigate the localisation of these aquaporin isoforms in the uterus during early pregnancy. AQP1 was localised to the myometrium and was shown to increase at the time of implantation while AQP5 was seen in the apical plasma membrane of luminal epithelial cells at the time of implantation. Both AQP5 and AQP9 were localised to the glandular epithelial cells, with AQP5 appearing at the time of implantation. Fluid reabsorption at the time of implantation thus may be mediated by AQP5 channels in the apical plasma membrane of luminal and glandular epithelial cells. It is also likely that AQP9 plays a role in reabsoprtion of glandular fluid. These results also suggest that AQP1 in the myometrium could facilitate fluid absorption into the muscle leading to swelling and mechanically closing down the uterine lumen around an implanting blastocyst.
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ISMO Commonly prescribed for Angina, Heart Attack, Coronary Bypass or Angioplasty. Continued use may indicate that the condition is not yet stabilized and the patient is at high risk. Blood Thinners Aggrenox Persantine Ticlid Coummadin Plavix Commonly prescribed following heart surgery, heart attack, stroke, or atrial fibrillation. Irregular Heart Beat Altace Lanoxin Rythmol Betapace Lopresso Sectrol Blocarden Mexitil Tambocor Calan Norpace Tenormin Cordarone Procanbid Tikosyn Coreg Quinaglute Tonocard Inderal Quinidex Toprol XL The condition can range from minor to extremely serious. Try to learn why the client is taking the medication, what led to the diagnosis, are there other underlying medical problems. Diabetes Oral ; Medications Actos Glucagon Glyset Amaryl Glucophage XR Micronese Avandia Glucotrol XL Prandin Diabeta Glucovante Precose Diabinese Glynase Most diabetics are over age 45 and can be successfully treated with oral medications. Many of them are eligible for Standard Life Insurance. Claudication Medications Pletal Trental Moderate blockage of the leg arteries is usually not terribly significant, severe blockage can be quite serious and may require surgery. Dementia or Alzheimer's Aricept Exelon Reminyl Cognex Hydergine Advanced cases of Alzheimer's are of course uninsurable, however too many physicians will prescribe these medications in very early cases or where family history indicates a possibility of Alzheimer's. These cases will be insurable and you would be negligent to assume that they are uninsurable. Cancer Medications Alkeran Estratab Lupron Arimidex Eulexin Megace Aromasin Fareston Menest Casodex Femara Nolvadex Cytoxan Gleevec Viadur Estinyl Hydrea Xeloda Estrace Leukeran Zoladex Cancer patients are insurable once they are in remission cancer free ; for two to five years following treatment. Continued use of any of these medications except for Arimidex, Femara, or Nolvadex ; indicates that they are not in remission. Parkinson's Medications Artane Mirapex Sinemet CR Cogentin Parlodel Symmetrel Comtan Perma Tasmar Eldeprly Requip Parkinson's usually progresses very slowly, however rapid deterioration is not uncommon. Many sufferers in the early stages of the disease are insurable on some reasonable basis. In order to evaluate the insurability of most applicants you need to know what Medications are currently being taken. You should get into the habit of asking every applicant about ALL medications, herbal supplements, and over-the-counter drugs that they are taking, dosages, why, and for how long has it is been taken. Please call us if you are not sure of the significance of your client's medication.
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Hofmeyr GJ 1. 2. Editor, Cochrane Pregnancy and Childbirth Group. 2004 Regional Editor, World Health Organization Reproduction Health Library. 2001.
COUMADIN COZAAR CREON CRESTOR cromolyn 4% ophthalmic drops cromolyn nebulized solution cyclobenzaprine CYMBALTA CYTOMEL --D-- DANTRIUM DEPAKENE DEPAKOTE DEPAKOTE ER desipramine desmopressin desonide 0.05% cream desonide 0.05% lotion desonide 0.05% ointment desoximetasone 0.25% cream DETROL DETROL LA dexamethasone dextromethorphan promethazine [Promethazine w DM] dextromethorphan pseudoephedrine brompheniramine [Cardec DM] DIASTAT diazepam diclofenac sodium dicloxacillin dicyclomine DIFFERIN diflunisal digoxin [Digitek] DILANTIN diltiazem ext-rel [Cartia XT, Dilt XR, Diltia XT, Taztia XT] diphenoxylate atropine [Lonox] DIPROLENE LOTION dipyridamole DOSTINEX DOVONEX doxazosin doxepin and cyclobenzaprine.
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Flutamide floo' ta mide ; is a drug that is used to treat prostate cancer. It blocks the effect of testosterone which is a male sex hormone that may stimulate the growth of prostate cancer. Flutamide is often used with another drug that lowers testosterone levels. It is a tablet that you take by mouth. The tablet contains lactose. It is important to take flutamide exactly as directed by your doctor. Make sure you understand the directions. You may take flutamide with food or on an empty stomach. If you miss a dose of flutamide, take it as soon as you can if it is within 4 hours of the missed dose. If it is over 4 hours since your missed dose, skip the missed dose and go back to your usual dosing times. Other drugs such as warfarin COUMADIN ; may interact with flutamide. Tell your doctor if you are taking this or any other drugs as you may need extra blood tests or your dose may need to be changed. Check with your doctor or pharmacist before you start or stop taking any other drugs. Avoid grapefruit and grapefruit juice for the duration of your treatment, as these may interact with flutamide. The drinking of alcohol in small amounts ; does not appear to affect the safety or usefulness of flutamide. Flutamide may lower sperm counts after you have taken it for a long time. If you plan to have children, discuss this with your doctor before taking flutamide. Store flutamide tablets out of the reach of children, at room temperature, away from heat, light, and moisture. Tell doctors or dentists that you are being treated with flutamide before you receive any treatment from them.
Larger prostatic ducts in the periurethral region. They grow with a papillary or cribriform pattern and frequently contain a mixture of the two architectural types. The tumor cells are columnar with pseudostratification and show substantial nuclear anaplasia, with large nuclei having coarse chromatin, prominent nucleoli, and frequent mitoses. In general, ductal adenocarcinomas are graded as Gleason pattern 77 ; , but comedonecrosis is common in this pattern and, when present, indicates a Gleason grade of 5 pure tumors almost always receive a Gleason score of 8 or The tumors stain positive for PSA and PAP, findings that help differentiate them from transitional cell carcinoma and secondary involvement of the prostate by colon carcinoma. Small cell carcinoma Fig 7 ; is a rare variant of prostate carcinoma that may occur de novo but more often manifests in a patient with known prostate cancer in whom the disease and detrol.
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This Rider provides payment for eligible prescription drug charges. You will pay a $15 copayment per prescription, or 20% of the prescription charge, whichever is greater, at the time you purchase the prescription. Unless your doctor requires the use of a brand name drug, your prescription will be filled with a generic when available and permissible by Oregon law. If you request a brand name drug when a generic drug is available, you are required to pay the copayment plus the difference in cost between the brand name drug and its generic equivalent. The following drugs may be filled with the brand name without the added cost to you: Coumadin, Dilantin, Lanoxin, Levothyroxine branded products, Norpace CR, Premarin, Procanbid, Quinaglute, Quinidex, Tegtretol, Tegtretol XR and Theodur. ; COVERED EXPENSES A covered expense is a charge that meets all of the following tests and dilantin.
Chlorpropamide 21 Chlorthalidone 60 Chlorzoxazone 86 Chol Sal Magnesium Salicylate 3, 4 CHOLELITHOLYTIC AGENTS 55 Cholesterol Absorption Inhibitors 35 CHOLESTYRAMINE 34 CHOLESTYRAMINE LIGHT 34 Cholestyramine Aspartame 34, 35 Cholestyramine Sucrose 34 CHOLINE MAG TRISALICYLATE 3 CHOREX-10 66 CHORIONIC GONADOTROPIN 66 Ciclopirox 27, 28 Cidofovir 47 Cilostazol 42 CILOXAN 25 CIMETIDINE 42 Cimetidine HCL 42 Cinacalcet HCL 72 CIPRO 15 CIPRO HC 25 CIPRO I.V. 15 CIPRO XR 15 CIPRODEX 25 Ciprofloxacin 15 Ciprofloxacin HCL 15, 25 Ciprofloxacin HCL Dexameth 25 Ciprofloxacin HCL HC 25 Ciprofloxacin HCL-Betaine Comb 15 Ciprofloxacin Lactate 15 Ciprofloxacin Lactate D5W 15 Cisplatin 37 CITALOPRAM 78 CITALOPRAM HBR 78 Citalopram Hydrobromide 78 Citric Acid Potassium Citrate 2 Cladribine 37, 39 CLAFORAN 11 CLAFORAN GALAXY 11 CLARAVIS 86 CLARINEX 85 CLARINEX-D 24 HOUR 85 Clarithromycin 12 Clemastine Fumarate 63 132 CLEOCIN 27 CLEOCIN HCL 10 CLEOCIN PHOSPHATE IN D5W 10 CLIMARA 62 CLINDAGEL 27 CLINDAMAX 27 Clindamycin HCL 10 Clindamycin Phosphate 10, 27 Clindamycin Phosphate D5W 10 CLINDESSE 27 CLINDETS 27 CLINIMIX 51 CLINIMIX E 51 CLOBETASOL E 32 CLOBETASOL PROPIONATE 32 Clobetasol Propionate Emoll 32, 33 CLOBEVATE 32 Clofarabine 37 CLOLAR 37 Clomipramine HCL 78 Clonidine HCL 67 Clonidine HCL Chlorthalidone 67 Clopidogrel Bisulfate 42 CLORPRES 67 Clotrimazole 28 CLOTRIMAZOLE 3 28 Clotrimazole Betamet Diprop 28 CLOTRIMAZOLE BETAMETHASONE 28 Clozapine 79 Codeine Phos Acetaminophen 4, 5, 7 Codeine Phos Aspirin 5 COGENTIN 18 CO-GESIC 5 COGNEX 76 COLAZAL 31 Colchicine 71 Colesevelam HCL 34 COLESTID 34 Colestipol HCL 34 Colistimethate Sodium 10 Collagenase 87 COLOCORT 32 COLYTE 54 COLYTE WITH FLAVOR PACKETS 54 COLYTROL 17 COMBIVENT 88 COMBIVIR 44 COMPRO 23 COMTAN 55 COMVAX 91 CO-NATAL FA 73 CONCERTA 8 CONDYLOX 86 CONSTULOSE 3 CONTRACEPTIVES 56 COPAXONE 71 CORDARONE I.V. 53 COREG 48 CORMAX 32 CORTEF 1 Corticosteroids EENT ; 29 Cortisone Acetate 1 CORTOMYCIN 25 CORZIDE 48 COSMEGEN 37 COSOPT 52 COUMADIN 42 COVERA-HS 49 COZAAR 81 CREON 10 58 CREON 20 58 CREON 5 58 CRESTOR 40mg ; 35 CRESTOR 5mg, 10mg, 20mg ; 35 CRIXIVAN 44 CROLOM 9 Cromolyn Sodium 9, 71, 72 CRYSELLE 56 CUBICIN 10 CUPRIMINE 66 CUTIVATE 32 Cyclobenzaprine HCL 86 Cyclophosphamide 37, 28 Cycloserine 37 Cyclosporine 30, 71 Cyclosporine, Modified 71, 72 CYKLOKAPRON 24 CYMBALTA 78 Cyproheptadine HCL 63 CYSTADANE 71.
You may be asked to leave our Plan in the following circumstances: If you behave in a way that seriously affects our ability to arrange or provide services for you or for others who are members of our Plan. We cannot make you leave i.e., disenroll from ; our Plan for this reason unless we get permission first from the Centers for Medicare & Medicaid Services, the government agency that runs Medicare. If you give us information on your enrollment form that you know is false or deliberately misleading, and it affects whether or not you can enroll in our Plan. If you let someone else use your Plan membership card to get prescription drugs for themselves or for others. Before we ask you to leave i.e., disenroll from ; our Plan for this reason, we must refer your case to the Inspector General, and this may result in criminal prosecution and diovan.
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Background: Lupron is a prescription drug that is manufactured, marketed, and sold by Abbott Laboratories, Takeda Chemical Industries, and TAP Pharmaceuticals a wholly owned joint venture of Abbott and Takeda ; as a treatment for prostate cancer. In September 2001, PAL filed suit alleging that the Defendants created and implemented a fraudulent marketing and sales scheme to substantially increase the sale of Lupron and reap unlawful profits at the expense of Medicare patients. The following month October 2001 ; TAP pharmaceuticals agreed to settle a criminal case brought against it by the federal government, pleading guilty and agreeing to pay $875 million. This was the largest health care fraud settlement in history. Update: PAL's and other attorneys have reviewed hundreds of boxes of defendants' documents and are set to continue with the discovery process, including conducting numerous depositions.
Tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other antibiotics, allopurinol lopurin ; , anticoagulants 'blood thinners' ; such as warfarin xoumadin ; , oral contraceptives, probenecid benemid ; , and vitamins and elocon.
Treatment is unclear. While levels of the gene encoding its activating enzyme, Ckb, were substantially raised by treatment bringing levels of transcription in R6 2 triple-treated mice close to that seen in WT mice ; , in R6 2 mice treated with creatine alone, behavioural improvements were limited. This is consistent with findings from a recent trial where creatine did not improve functional or cognitive status of HD patients after a year of treatment Verbessem et al., 2003 ; . However, as we saw no deleterious effects of creatine either alone or in combination with any other drug, it seems likely that combination therapies could be used safely in patients alongside creatine supplements. Although the drugs we used have a global effect on ACh and NA levels, the behavioural improvements appear to be relatively specific. In particular, the deficits alleviated by the triple treatment improved cognitive rather than motor performance. In both cognitive tasks, the improvements were primarily in performance of the reversal of the tasks. This suggests a fronto-striatal locus for the beneficial effects. Although the Morris water maze is traditionally considered to be a `hippocampal' task, performance in this task is profoundly disrupted by prefrontal lesions Sutherland et al., 1982 ; . Further, delayed alternation in a T maze is the classic test of frontal function in rodents Sutherland et al., 1982 ; , and in a variety of tasks, disruption of response selection, including perseverative deficits, is a hallmark of fronto-striatal disturbance Kolb et al., 1975; Ridley et al., 1993; Dunnett et al., 1999 ; . It is particularly interesting that the perseverative behaviours that improved in the R6 2 mouse after triple treatment have human correlates that are found in HD. Visuospatial deficits are one of the earliest cognitive changes in HD Lawrence et al., 1996 ; , and perseverative behaviour has been reported in HD patients in a number of tasks including Wisconsin card sorting tests, attention set shifting tests, and spatial working memory tasks Lawrence et al., 1996, 1999; for other references, see Bates et al., 2002 ; . Obsessive-compulsive disorder, arguably considered as a type of perseverative behaviour, is also found in HD patients Anderson et al., 2001 ; . Therefore, the triple treatment approach used for our mice might be particularly useful for treating perseverative behaviours in HD patients. Because cognitive dysfunction in the R6 2 mouse progresses separately from motor deterioration, attention should be paid to combining drugs that improve cognitive function with drugs that may also ameliorate motor symptoms. Such drugs might include those that improve abnormal spontaneous and drug-induced locomotor symptoms without impairing cognition, such as endocannabinoid uptake inhibitors Lastres-Becker et al., 2002 ; or dual muscarinic receptor agonist dopamine receptor antagonists. Future pharmacological targets should include not only postsynaptic mechanisms involved in neurotransmitter breakdown, but also proteins that modulate the release of transmitter from the presynaptic terminal, such as the complexins Morton & Edwardson, 2001 ; , and the other genes with synaptic roles that showed expression modulated by treatment in this study. A number of previous studies describe the changes in gene expression in mouse models of HD Luthi-Carter et al., 2000, 2002a, 2002b; for other references see Bates et al., 2002 ; but it is not possible to tell which of the gene changes are primary pathological changes in response to the mutation ; , which are secondary pathological changes and which might be beneficial compensatory changes. For our array study, we looked at only a single timepoint 8 weeks ; , when the changes in gene expression in the R6 2 mouse are modest. By 12 weeks of age, many more genes are dysregulated in the R6 2 mouse Luthi-Carter et al., 2000, 2002a, 2002b; Orr, 2002 ; . Comparison of the changes seen in the R6 2 mouse brain compared with WT littermates in the current study with those seen in the striatum by Luthi-Carter et al. 2002a ; shows that 75% of the genes they detect as.
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Additional sources: EMEA identifier no. 51 Patient: Date of entry: Adverse effect: Preparation: Co-medication: Female, 44 years of age 9 March 2001 Elevated liver enzymes Combination of kava and vitamin B1, B6 and niacin, unknown dosage Anticoagulation: 5 mg of warfarin Coumadun ; , unknown duration; Major tranquilizer: Citalopram hydrobromide Celexa NSAID: Celecoxib Celebryx ; , dosage and duration unknown, Pain relief: Oxycodon OxyContin ; , dosage and duration unknown; Estrogen: dosage, application form and duration unknown. Outcome: The case involved a patient with Marfan syndrome complaining of chest and back pain.
Have you ever been diagnosed with: yes no artificial heart valves yes no artificial joints, screws yes no bleeding abnormally yes no blood disease yes no congenital heart lesions yes no heart murmur yes no hernia repair yes no mitral valve prolapse yes no pacemaker yes no rheumatic fever Have you ever taken any of these medications? yes no blood thinners coumadin, warfarin ; yes no diet medications dexfenfluramine, fen-phen, pondimin, redux ; yes no levoxyl.
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4. Review current labor status, OB, and medical history for risk factors. INTERVENTIONS: 5. Select interventions to treat underlying pathophysiology. NOTE: It is not necessary to proceed with subsequent steps if current intervention corrects a non-reassuring FHR pattern. 6. Change maternal position: laterally, then to all fours or knee chest. Correct maternal hypotension: move patient out of supine position, check blood pressure, increase IV rate, elevate legs if not contraindicated. NOTE: For severe hypotension related to epidural, Anesthesiologist may give ephedrine IV. 8. 9. Discontinue oxytocin if infusing. Administer oxygen at 8-10 LPM via non-rebreather face mask.
3.1 Hepatitis B Exposure All significant exposures, see page 6 ; should be treated as if capable of transmitting hepatitis B. The table below gives advice on the use of both hepatitis B vaccine and high titre hepatitis B immunoglobulin HBIG ; in the various circumstances that may arise. 3.2 Hepatitis B surface Antigen HbsAg ; testing of the source will be performed, unless this is known from recent previous investigation. In most circumstances an HbsAg result will be available within 24-48 hours provided a source patient sample is sent after obtaining informed consent that should also include consent for HCV and HIV for all contaminated injuries ; . Pre-exposure HBV status of person exposed 1 dose HB vaccine.
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It shall be the discretion of the State to determine if hospital Pharmacy training experience is lieu of the ASHP Program is sufficient acceptable evidence of the requisite experience capabilities. e. The Contractor shall ensure that non-pharmacist personnel work only under the direct supervision of a pharmacist who is fully aware of all activities involved in the preparation and dispensing of medications, including the maintenance of appropriate records; that the duties and responsibilities on non-pharmacist personnel are consistent with their training and experience; and that nonpharmacist personnel are not assigned duties that by law must be performed only by licensed pharmacists. All personnel shall have an orientation program that addresses State and Federal Laws and appropriate professional standards. Copies of State and Federal.
The following drugs may reduce the effectiveness of tegretol: acetaminophen tylenol ; alprazolam xanax ; amytriptyline antianxiety medication such as ativan and valium antibiotics such as adriamycin and doryx antidepressants such as celexa, norpramin, remeron, and pamelor antipsychotics such as clozaril, zyprexa, risperdal, and geodon antiseizure medication such as felbatol, lamactil, topamax, and depakene bupropion wellbutrin, zyban ; calcium channel blockers such as plendil and sular cisplatin platinol ; citalopram celexa ; clobazam corticosteroids such as pediapred and decadron cyclosporine sandimmune ; delavirdine dicumarol ethosuximide felodipine plendil ; glucocorticoids haloperidol haldol ; itraconazole sporanox ; levothyroxine synthroid ; methadone methsuximide midazolam oral contraceptives phensuximide phenytoin praziquantel protease inhibitors such as crixivan, norvir, and viracept rifampin rifadin, rimactane ; theophylline theo-24, uniphyl ; tiagabine tramadol ultram ; triazolam halcion ; tricyclic antidepressants such as elavil, pamelor, and tofranil warfarin coumadin ; tegretol may increase the effectiveness of clomipramine hcl anafranil ; , phenytoin, or primidone if the drugs are taken together.
QL-23. ASSESSING THE INFORMATION AND SUPPORT NEEDS OF PARENTS WHOSE CHILDREN HAVE BRAIN TUMORS Jane R. Schubart and Elana Farace, Departments of Health Evaluation Sciences and Neurosurgery, University of Virginia, Charlottesville, VA, USA Introduction: The specific aim of our study was to conduct a needs analysis of the information and caregiving needs of parents of pediatric and young adult brain tumor patients for the purpose of developing a Web-based tool that is an innovative communication intervention designed specifically for them. Methods: Parents of children and young adults, ages 5 to 25, seen at the University of Virginia Neurosurgery Department and diagnosed with a brain neoplasm, of any grade, were included. Multiple inquiry methods were used to explore parental caregiver needs and concerns and identify possible solutions. Qualitative e.g., content analysis of interview transcripts ; and quantitative e.g., correlation of survey data ; methodologies were used to understand themes and compare respondent groups. Specific inquiry methods included 1 ; interviews with parents to collect data related to sources of information and unmet needs, 2 ; survey questionnaires, and 3 ; interviews with health care professionals. Results: Four main themes were identified. First, while most parents sought online information about brain tumors usually at the time of initial diagnosis ; , the information retrieved was of limited value. Although there are some useful resources on the Web, the resources developed specifically for brain tumor patients and families are lim.
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